Synthesis of α, β-Unsaturated Esters by Application of Wittig Reaction
نویسندگان
چکیده
منابع مشابه
Process for the synthesis of α, β-unsaturated esters
The present invention provides a process for the synthesis of an α,β-unsaturated ester from a mono-olefinester using Fe(CO).sub.5.
متن کاملApplication of the diastereoselective photodeconjugation of α,β-unsaturated esters to the synthesis of gymnastatin H
The asymmetric synthesis of gymnastatin H has been achieved by using the photoisomerisation of a conjugated ester to its β,γ-unsaturated isomer through the protonation of a in situ generated dienol as key step. Thanks to diacetone D-glucose used as a chiral alkoxy group, the protonation occurred well onto one of the two diastereotopic faces with very high yields and selectivities. Moreover, by ...
متن کاملSynthesis of α,β-unsaturated esters via a chemo-enzymatic chain elongation approach by combining carboxylic acid reduction and Wittig reaction
α,β-Unsaturated esters are versatile building blocks for organic synthesis and of significant importance for industrial applications. A great variety of synthetic methods have been developed, and quite a number of them use aldehydes as precursors. Herein we report a chemo-enzymatic chain elongation approach to access α,β-unsaturated esters by combining an enzymatic carboxylic acid reduction and...
متن کاملMicrowave assisted Pd(OAc)2-catalyzed chemoselective reduction of aryl α,β-unsaturated esters with triethylsilane
< p>In this communication, we have reported that the Pd(OAc)2–Et3SiH-DMF system promotes the microwave-assisted chemoselective reduction of aryl α,β-unsaturated esters in good yields. The protocol affords a convenient reduction of aryl-conjugated double bonds even in presence of other functional groups like esters, phenols, and ethers.
متن کاملNHC organocatalytic formal LUMO activation of α,β-unsaturated esters for reaction with enamides.
a,b-Unsaturated carbonyl compounds are basic building blocks in organic synthesis. Lewis acid catalysts bearing chiral ligands have traditionally been used for the asymmetric catalytic activation of this class of molecules as Michael acceptors. Indeed, Lewis acid catalysis continues to be a powerful approach in which innovative solutions are still emerging. Representative examples of chiral Lew...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1960
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.8.819